There are some who even contend that it can improve cogni… Results need to be supported using lower doses of lemon balm extracts. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Lemon Balm Tea (Bulk Herbal Tea): Bulk Lemon Balm Leaf (Melissa Officinalis Caffeine Free) - Herbal Balm, Bulk Balm Leaf (Cut and Sifted), 1lb (16Oz) 4.5 out of 5 stars 102. Disclaimer: All information contained on this website is for educational and informational purposes only and is based on traditional usage and research articles. Benefits to mood, cognition, and memory also have been supported in vitro, with acetylcholinesterase (AChE) inhibition seen as especially relevant. It is indigenous to the Mediterranean region and western Asia, and widely naturalized in Europe, Asia, and North America. The Eastern Mediterranean region, Western Asia, Southern Europe, Caucasus, and northern Iran are considered its areas of origin, but it grows worldwide. Doses of 600 to 1,600 mg extract have been studied in trials. SPL UNCLASSIFIED SECTION Gaia Herbs, Inc., 101 Gaia Herbs Drive, Brevard, NC 28712 Plants are a rich source of phytochemicals that have a variety of pharmacological activities. One small study demonstrated decreased stress and agitation in patients with dementia and Alzheimer disease. Microbial metabolites of RA may account for many of its activities. Lovely and interesting writing. Similarly, mean AST decreased 1.35 units/L with treatment and increased 2.23 units/L with placebo. The authors searched unpublished old texts and several databases of published literature to review the botanical characteristics, traditional uses, phytochemistry, pharmacology, pharmacokinetics, and toxicity of lemon balm. To make lemon balm tea, follow these simple steps. 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Neuroprotective effects of various fractions of lemon balm have been demonstrated in vitro and in vivo, with significant protection against oxidative stress and amyloid beta (Aβ)-induced toxicity. Melissa is traditionally used as an adaptogen all around the world. Studies suggest that lemon balm essential oil has the … This recipe contains lemon balm, an herb that some promising research indicates can boost mood and improve cognitive performance. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. Essential oil created from the leaves can also eaten and used as an antioxidant (Marangui et al., 2004). Research reveals little or no information regarding toxicology with the use of this product. A small trial evaluated the cardiac effects of lemon balm and reported possible cardiac muscarinic receptor stimulation or calcium channel-dependent blockage.38 Potentiation of pharmacologic agents may be possible. None well documented. In ADHD in children, researchers paired lemon balm with valerian root. Lemon balm supplements are widely available and are inexpensive; you can use the study above, 300 to 600mg daily, as a guideline. While its composition varies by region and climate, most studies report that LBEO contains oxygenated monoterpenes, including the citral isomers geranial and neral, as well as citronellal, geraniol, and geranyl acetate. The lyophilized hydroalcoholic extract, which does not contain the volatile oil components, exhibited sedative activity in several mouse models when given intraperitoneally.19 This extract was also active in an acetic acid writhing analgesia assay but not in a hot plate test. 28 In vitro analyses of the antimicrobial properties of lemon balm suggested that at a concentration of 500microg/mL, the … 1 2 3 4 Lemon balm has been used for medicine for thousands of years by many people in the Mediterranean. The plant has culinary and medicinal uses, with principal historical medicinal uses being carminative, diaphoretic, and antipyretic.2 A standardized preparation of lemon balm (80 mg) and valerian extract (160 mg) has been given 2 or 3 times/day as a sleep aid, and has also been studied in children. Lemon balm is high in flavonoids, which can have an antioxidant effect. Current evidence suggests that a daily oral dose of 600 mg lemon balm extract is possibly safe and effective in treating memory, mood, and cognition problems, and topical formulations containing 1% lemon balm are effective in treating very early stages of herpes simplex virus 1 and 2. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Lemon balm has also been shown to possess antimicrobial, antiviral, antispasmodic and antitumoral properties. None of these statements has been evaluated by the Food and Drug Administration. Lemon balm {also called beebalm} comes in a variety of shades which are perfect in the herbal garden. I like the contrast with borage. You can also grow lemon balm yourself. Its medicinal properties were first documented by Dioscorides (40-90 CE), who recommended a leaf decoction for spider, scorpion, and dog bites, and for amenorrhea, dysentery, mushroom poisoning, scrofulous tumors, and other indications. We may find ourselves asking an important, Herbs have caught the imagination of mankind ever since its advent on the earth. Baseline mean LDL dropped by 13.96 mg/dL with the intervention compared to a 1.17 mg/dL increase with placebo. Lemon balm’s rosmarinic acid (RA) component, with four hydroxyl groups, may be a stronger antioxidant than vitamin E or Trolox. Primary interest in lemon balm surrounds its effects on the central nervous system. Pediatric patients have displayed improvement in restlessness and dyssomnia with the ingestion of lemon balm extract. Lemon balm’s main active components are volatile compounds, triterpenes, and phenolics. Koetter, U., & Biendl, M. (2010). A novel pharmacological mechanism of action for the anxiolytic botanical Melissa officinalis L. (lemon balm) is reported. Contraindications have not yet been identified. Lemon balm was used by Avicenna (981-1037) for all diseases caused by black phlegm and black bile. In fact, the majority of drugs on the market are either from natural sources or have been inspired by compounds found in nature. Get it as soon as Fri, Dec 4. The volatile oil of the plant had much weaker activity or was inactive in the same assays. turmeric, echinacea, saw palmetto, milk thistle, Ginkgo Biloba. The name Melissa corresponds to the Greek word for bee, while balm is a contraction of balsam. The leaves are harvested before flowering and used medicinally.1, Lemon balm has been used in herbal medicine since the times of Pliny (Roman, AD 23-79), Dioscorides (Greek, AD 40-90), Paracelsus (Austrian 1493-1541), and John Gerard (English, 1545-1612). Lemon balm is a lemony plant that’s commonly used in teas and seasonings. Crooked Bear Creek Organic Herbs abides by the National Association for Holistic Aromatherapy’s Code of Ethics. In the event of an essential oil, poisoning calls Poison Control immediately. None of this information is intended to replace the services of a qualified healthcare practitioner. Enter your email address to follow this blog and receive notifications of new posts by email. The plant has also been reported to be used as a cardiac and gastric tonic, memory enhancer, wound disinfectant, and for certain eye diseases. In other words, … Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). It Can Calm You. Much remains unknown about the bioavailability of lemon balm extracts and components. Myrrh Oil; USES OF MYRRH – PURIFICATION, PERFUMERY & MORE! They have been admired for their beauty and fragrance, and, These two recipes are prepared as teas but are not taken in your tea cup – they help with the discomfort of flu season in, Copyright © Crooked Bear Creek Organic Herbs 2014-2020. Abstract Lemon balm (Melissa officinalis) has been used historically and contemporarily as a modulator of mood and cognitive function, with anxiolytic effects following administration of capsules, coated tablets and topical application. FREE Shipping on orders over $25 shipped by Amazon. Phenylpropanoids including hydroxycinnamic acid derivatives such as caffeic and chlorogenic acids and in particular rosmarinic acid (up to 6%) [ESCOP, 2003; WHO monograph s, 2002]. The Bacopa monniera herb, also known as Brahmi, has been, Whether you are collecting the flowers, leaves or stems, you, With its bright green stalks and vibrant, lavender-pink and spiky, As winter slowly winds down, many gardeners cannot wait to, There’s good news for sufferers of upper respiratory ailments. Microbial metabolites of RA may account for many of its activities. While lemon balm has been reported to be relatively well tolerated in humans when used for up to eight weeks, some adverse effects have been noted with both oral and topical administration. It is a component of about 400 ITM medicinal preparations. He attributed its antidepressant effects to its aroma. Future research needs include mechanisms of action, efficacy, and proper dosages for other ethnomedical uses of lemon balm, as well as proof-of-concept clinical trials evaluating its usefulness as an adjunct to conventional treatment for depression. The name Melissa corresponds to the Greek word for bee, while balm is a contraction of balsam. Since 1984, it has been listed in the German Commission E monographs and is included in several pharmacopeias. Pliny, Hippocrates, Galen, Culpepper, and even Shakespeare all spoke of its attributes. In Danish folk medicine, lemon balm is used for sleeplessness caused by heartbreak or melancholy; in Austria, its essential oil (LBEO) is used for gastrointestinal, nervous, hepatic, and biliary problems. Protects against heart and liver problems. Lemon balm has antiviral activity against a variety of viruses, including herpes simplex virus (HSV) and HIV-1.11, 12 The activity has been attributed to caffeic acid and its di- and trimeric derivatives, as well as to tannins. The methanol extract was identified as a potent in vitro inhibitor of rat brain GABA transaminase (GABA-T), an enzyme target in the therapy of … This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. No serious adverse events were reported.41. It can help relieve stress. Herbal Pharmacology Herbal Pharmacology. Lemon balm is a low-growing perennial herb with ovate- or heart-shaped leaves that emit a lemon odor when bruised. In a series of trials investigating the effects of lemon balm extract on laboratory-induced stress, a dose-dependent effect was demonstrated for single doses of Melissa officinalis.2, 20, 21 Cholinergic receptor-binding properties have also been demonstrated.20 With 600 mg of extract, increased calmness and decreased alertness were demonstrated compared with placebo. A 1% extract cream has been studied as a topical agent for treatment of herpes virus lesions. Essential oils made from lemon balm leaves contain plant chemicals called terpenes, which play at least some role in the herb's relaxing and antiviral effects. The placebo group in this randomized trial (n = 100) also experienced a significant improvement in sleep scores compared with baseline (P = 0.0001). Thank you for reading the posts and you are welcome. [1] Bonus: It can help you feel less stressed without making you feel sleepy or drugged—and that can mean better energy to enjoy your better mood. Post was not sent - check your email addresses! None of these products is intended to diagnose, treat, cure or prevent any disease. Lemon Balm Leaf; In vitro studies reveal lemon balm’s inhibition of several human cancer cell lines, but a great deal of research needs to be conducted before any clinical applicability could be assessed. Lemon balm’s cardiovascular, cytotoxic, anti-inflammatory, antinociceptive, hypoglycemic, hypolipidemic, antioxidant, antimicrobial, antiviral, antispasmodic, antiangiogenic, and antiepileptic effects all have support in various research models, with the general proviso that many doses used in animal trials cannot realistically be applied in clinical practice. Lemon balm is said to soothe symptoms of stress, help you to relax, and … Inactive ingredients Organic Glycerin, Organic Lemon Balm Extract, Organic Lemon Essential Oil, Purified Water USP. Lemon balm extract is a … Since 2014, Crooked Bear Creek Organic Herbs Has Become The Forefront In Herbal Knowledge. It's POSSIBLY SAFE in adults when taken by mouth or applied to the skin in medicinal amounts, short-term. Human clinical trials have shown that lemon balm can relieve agitation in people with dementia and improve the mood and stress levels of healthy adults. Lemon balm supplements are made from the leaves of the plant. It contains … Scientific Name(s): Melissa officinalis L.Common Name(s): Balm, Lemon balm, Melissa, Sweet balm. Stress Relief. Antidepressive effects of lemon balm need more study, especially the monoamine oxidase A (MAO-A) inhibitory activity of compounds other than RA. If your life is governed by anxiety and stress, you can reap the benefits of lemon … Alternative practitioners believe that lemon balm can be used to treat a wide range of medical conditions, including insomnia, cold sores, high cholesterol, genital herpes, heartburn, and indigestion. Let’s Create Some Herbal Remedies – When Cold and Flu Season Arrives. Most clinical trials report no adverse reactions.2, 20, 37, Melissa extract was not found to be genotoxic in a screen of several medicinal plants.39. Antioxidant and antimicrobial effects also are attributed to its triterpenes. Chaparral, Now, More Than Ever, It’s Important to Stay Healthy at Home. Orange Essential Oil May Improve Symptoms of PTSD, “Organic Essential Oils,” USDA Organic Certification and Seal, PROBLEMS WITH USING ESSENTIAL OILS LIKE DRUGS, Safe and Effective Use of Essential Oils: What You Need to Know About What You’re Not Being Told, PROBLEMS WITH SELLING ESSENTIAL OILS LIKE DRUGS, Study Evaluates Seven Helichrysum Species for Volatile Profile and Essential Oil Composition, THE THEORY & PRACTICE OF ESSENTIAL OIL BLENDING, The Tranquility Oil; Vetiver Essential Oil. May Aid Diabetes Treatment. LBEO, widely used in the pharmaceutical and food industries, is considered to be responsible for lemon balm’s antibacterial and antifungal effects. Lemon balm has been used in herbal medicine since the times of Pliny (Roman, AD 23-79), Dioscorides (Greek, AD 40-90), Paracelsus (Austrian 1493-1541), and John Gerard (English, 1545-1612). Traditional uses of lemon balm have been supported by its pharmacological anxiolytic effects, possibly due to gamma-aminobutyric acid transaminase (GABA-T) inhibition and/or reduced levels of corticosterone. Antibacterial/antifungal effects: The lemon balm constituent rosmarinic acid was reported to impair in vivo activation of mouse macrophages by heat-killed Corynebacterium parvum, as measured by the decreased capacity of the activated macrophages to undergo the oxidative burst. [7] [30] [31] [32] The composition and pharmacology and potential uses of lemon balm have been extensively studied, especially with regard to its traditional uses. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Phenolic compounds in lemon balm, including derivatives of benzoic and caffeic acids, likely exert antioxidant and free radical scavenging effects. The essential oil made from lemon balm is high in compounds called triterpenes, which are rapidly absorbed through the lungs and have a calming effect on the body through aroma therapy. This information relates to an herbal, vitamin, mineral or other dietary supplement. The American Association of Poison Control Centers hotline is available 24 hours a day, 7 days a week at 1-800-222-1222. Lemon balm contains substances called tannins, which may be responsible for many of the herb's antiviral effects. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Lemon balm tincture taken daily and lemon balm cream applied topically long-term, improved quality of life and decreased dementia ratings in seniors in two separate studies (Akhondzadeh et al., 2003; Ballard et al., 2002). In vivo studies were supported by two human clinical trials; however, more randomized clinical trials (RCTs) are needed to better understand its mechanisms of action. Lemon balm’s cardiovascular, cytotoxic, anti-inflammatory, antinociceptive, hypoglycemic, hypolipidemic, antioxidant, antimicrobial, antiviral, antispasmodic, antiangiogenic, and antiepileptic effects all have support in various research models, with the general proviso that many doses used in animal trials cannot realistically be applied in clinical practice. There are few pharmacokinetic studies of lemon balm, with most focusing on its hydrocinnamic acid derivatives, especially RA, absorbed via paracellular diffusion. Doses of 600 to 1,600 mg have been studied in trials. Care should be exercised with regard to high dosage or prolonged use until in-depth evidence from toxicity and dose-escalation studies are available. The plant has culinary and medicinal uses, with principal historical medicinal uses being carminative, diaphoretic, and antipyretic.2, Lemon balm leaves contain 0.2% to 0.3% of a lemon-scented essential oil similar to that of lemon grass. I grow and use lemon balm for tea or to use a part of a tea brew from the garden. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. National Association for Holistic Aromatherapy’s Code of Ethics. Select one or more newsletters to continue. Not enough is known about the safety of lemon balm when used long-term. gabriela.mazzanti@uniroma1.it Melissa officinalis L. (Lamiaceae) (lemon balm) is used in folk medicine for nervous complaints, lower abdominal … By Amazon market are either from natural sources or have been studied in trials (... [ 33 ] flavonoids with glycosides of luteolin, quercetin, apigenin and kaempferol ESCOP. 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